Background: Regarding to sedentary lifestyle and its early complications, electro diagnostic studies can have valuable effects on prevention, diagnosis, follow up and treatment of neuromuscular disorders. This Study aimed to compare Nerve Conduction velocity (NCV) of the posterior tibial Nerve in athletes and nonathletes materials and Methods: Totally 237 university students, 124 with appropriate exercise activity from physical education students and 113 without appropriate physical activity from medical students were se1ceted. General data and data related to NCV of posterior tibial Nerves in two groups were collected using a previously designed questionaire and neurogram test. Data were analysed by SPSS software using Mann- whithny test in order to compare means. Results: The results showed NCV of right and left on posterior tibial Nerves in female students were more than male ones (P= 0.041, P=0.012 respectively). NCV of the right and left tibial in athletes and nonathletes females had not statistical differences (P=0.149, P=0/961 respectively). In male students there were significant differences in NCV of right and left tibial Nerves of athletes and nonathletes (P=0.001) Conclusion: In regard to effect of exercise on increasing NCV and reducing reflective time, it is necessary that physical education centers improve their educational programes.